What is pruritus?
Pruritus—the medical term for itching—is an unpleasant skin sensation that leads to scratching. It is frequently associated with chronic kidney disease (CKD).
What are some of the effects of pruritus in CKD patients?
Chronic pruritus can affect people in many ways beyond the serious itching:
- Serious skin irritation/bleeding from scratching
- Feeling embarrassed about your itching
- Trouble sleeping at night
- Tiredness during the day
- Feeling isolated or depressed
What is CKD-aP?
Chronic kidney disease–associated pruritus (CKD-aP) is the itching you may experience with CKD or end-stage renal disease (ESRD).
How common is pruritus in chronic kidney disease patients?
The actual number of people suffering from CKD-aP is difficult to know. For one thing, doctors may underestimate and underreport how many people are suffering from CKD-aP. Also, people with CKD-aP often don’t talk about their itching with their doctor. Best estimates are that CKD-aP impacts up to 65% of people with CKD undergoing dialysis in the US. Up to 33% of those with CKD undergoing dialysis in the US say they are moderately to extremely bothered by itching.
Can CKD-aP be treated?
CKD-aP can be difficult to diagnose. In fact, there is no specific test for CKD-aP, so doctors often diagnose it by ruling out other possible conditions. So, it’s important that you let your healthcare team know how bad your itching is—that can be key to diagnosis.
If you are diagnosed, the good news is that there is now a treatment available! KORSUVA received Breakthrough Therapy Designation from the FDA and is the first and only FDA-approved treatment specifically designed to take on the itch for adult hemodialysis patients suffering from moderate-to-severe chronic kidney disease–associated pruritus (CKD-aP).
What is KORSUVA?
KORSUVA is the first and only FDA-approved treatment specifically designed to take on the itch for adult hemodialysis patients suffering from moderate-to-severe chronic kidney disease–associated pruritus (CKD-aP).
How do I take KORSUVA?
KORSUVA is given as an injection into your IV line at the end of each dialysis treatment.
What are the possible side effects of KORSUVA?
KORSUVA was generally well tolerated in clinical trials involving over 1300 patients. The side effects reported most frequently by people receiving KORSUVA were diarrhea, dizziness, nausea, trouble walking (including falls), high potassium, headache, sleepiness, and mental status change (including confusional state). Learn more about KORSUVA safety and side effects here.
Does dialysis affect my itching?
It may seem like your CKD-aP is worse when you’re undergoing dialysis. But that doesn’t mean you should stop your dialysis or go less often. In fact:
- People missing dialysis have higher rates of infection from bacteria and a decline in general health.
- Missing 1 or more dialysis treatments in a 4-month period can lead to hospitalization—and possibly even death.