In clinical trials with over 850 adults on hemodialysis with moderate-to-severe chronic kidney disease–associated pruritus (CKD-aP), KORSUVA was proven to help achieve and maintain itch relief.
Less itching
Patients who received KORSUVA experienced itch relief by week 4 of treatment.
In 2 clinical trials studying over 850 hemodialysis patients, more patients who received KORSUVA improved their itchiness compared with those who received placebo.
Patients who received KORSUVA experienced itch relief by week 4 of treatment.
In 2 clinical trials studying over 850 hemodialysis patients, more patients who received KORSUVA improved their itchiness compared with those who received placebo.
Lasting relief
Patients who received KORSUVA experienced sustained itch relief through week 12 of treatment.
In 2 clinical trials studying over 850 hemodialysis patients, more patients who received KORSUVA experienced sustained itch relief at 12 weeks compared with those who received placebo.
Patients who received KORSUVA experienced sustained itch relief through week 12 of treatment.
In 2 clinical trials studying over 850 hemodialysis patients, more patients who received KORSUVA experienced sustained itch relief at 12 weeks compared with those who received placebo.
Ready to talk to your healthcare team about KORSUVA?
About the clinical studies
KORSUVA clinical trials measured itching using a simple, validated, patient-reported scale of itching.
Study size
Two clinical trials to study the efficacy of KORSUVA involved a diverse population of 851 hemodialysis patients with moderate-to-severe CKD-aP.
Who was studied
- All patients studied had confirmed moderate-to-severe CKD-aP
- The average age was 59 years
- The age range was from 22 to 88 years old
- In both studies combined:
- — Approximately 40% of people were female
- — Approximately 30% of people were Black or African American
Safety and side effects
The safety of KORSUVA was studied in over 1300 people undergoing dialysis with moderate-to-severe pruritus. In the 2 trials studying 851 patients, less than 5% of people receiving KORSUVA reported feeling serious side effects (compared with 2.8% of people who received placebo), and less than 3% of people stopped treatment as a result of feeling side effects (compared with 0.7% of people who received placebo). The side effects reported most frequently by people receiving KORSUVA were diarrhea, dizziness, nausea, trouble walking (including falls), high potassium, headache, sleepiness, and mental status changes (including confusional state).
Learn more about safety and side effects here.
Stay informed
Get the latest about KORSUVA and living with the itch of CKD-aP.
WHAT IS KORSUVA?
KORSUVA is a prescription medicine used to treat moderate-to-severe pruritus (itching) associated with chronic kidney disease (CKD-aP) in adults undergoing hemodialysis (HD).
KORSUVA is not recommended in patients undergoing peritoneal dialysis (fluid taken from abdomen).
IMPORTANT SAFETY INFORMATION
What are the possible side effects of KORSUVA?
KORSUVA may cause serious side effects, including:
- Dizziness, sleepiness, mental status changes (e.g., confusion), and trouble walking (which may lead to falls). Sleepiness is more likely to occur in patients who are 65 years or older. Taking KORSUVA with centrally acting depressant medications (including anti-depressants and medicines used for anxiety, epilepsy, insomnia), sedating antihistamines (allergy medicines that can cause drowsiness), and opioid analgesics (certain pain medications) may increase the likelihood of these side effects.
- Impairment of mental or physical abilities. You should not drive or operate dangerous machinery until the effect of KORSUVA on your ability to drive or operate machinery is known. The most common side effects of KORSUVA include: diarrhea, dizziness, nausea, trouble walking (including falls), high potassium, headache, sleepiness, and mental status changes (e.g., confusion).
What should I tell my doctor before taking KORSUVA?
Before you take KORSUVA, tell your doctor if you:
- are currently taking centrally acting depressant medications (including anti-depressants and medicines used for anxiety, epilepsy, insomnia), sedating antihistamines (allergy medicines that can cause drowsiness) or opioid analgesics (certain pain medications)
- regularly drive or operate dangerous machinery
Know the medicines you take. Keep a list of them to show your doctor and pharmacist when you get a new medicine. Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Tell your doctor if you are pregnant or breastfeeding or plan to become pregnant or breastfeed. In pre-clinical studies, KORSUVA was shown to be transferable into breastmilk.
Tell your doctor if you have any side effect that bothers you or does not go away. These are not all of the possible side effects of KORSUVA. You may report side effects to Vifor (International) Inc. at
1-844-835-8277 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.
The risk information provided here is not comprehensive and does not take the place of talking with your doctor about your medical condition or treatment. To learn more about KORSUVA, talk with your healthcare provider or pharmacist.
WHAT IS KORSUVA?
KORSUVA is a prescription medicine used to treat moderate-to-severe pruritus (itching) associated with chronic kidney disease (CKD-aP) in adults undergoing hemodialysis (HD).
KORSUVA is not recommended in patients undergoing peritoneal dialysis (fluid taken from abdomen).
IMPORTANT SAFETY INFORMATION
What are the possible side effects of KORSUVA?
KORSUVA may cause serious side effects, including:
- Dizziness, sleepiness, mental status changes (e.g., confusion), and trouble walking (which may lead to falls). Sleepiness is more likely to occur in patients who are 65 years or older. Taking KORSUVA with centrally acting depressant medications (including anti-depressants and medicines used for anxiety, epilepsy, insomnia), sedating antihistamines (allergy medicines that can cause drowsiness), and opioid analgesics (certain pain medications) may increase the likelihood of these side effects.
- Impairment of mental or physical abilities. You should not drive or operate dangerous machinery until the effect of KORSUVA on your ability to drive or operate machinery is known. The most common side effects of KORSUVA include: diarrhea, dizziness, nausea, trouble walking (including falls), high potassium, headache, sleepiness, and mental status changes (e.g., confusion).
What should I tell my doctor before taking KORSUVA?
Before you take KORSUVA, tell your doctor if you:
- are currently taking centrally acting depressant medications (including anti-depressants and medicines used for anxiety, epilepsy, insomnia), sedating antihistamines (allergy medicines that can cause drowsiness) or opioid analgesics (certain pain medications)
- regularly drive or operate dangerous machinery
Know the medicines you take. Keep a list of them to show your doctor and pharmacist when you get a new medicine. Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Tell your doctor if you are pregnant or breastfeeding or plan to become pregnant or breastfeed. In pre-clinical studies, KORSUVA was shown to be transferable into breastmilk.
Tell your doctor if you have any side effect that bothers you or does not go away. These are not all of the possible side effects of KORSUVA. You may report side effects to Vifor (International) Inc. at 1-844-835-8277 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.
The risk information provided here is not comprehensive and does not take the place of talking with your doctor about your medical condition or treatment. To learn more about KORSUVA, talk with your healthcare provider or pharmacist.